One of the hallmarks of aging is cellular senescence. Cells lose the ability to divide, differentiate, and replicate — yet stubbornly refuse to die.
These senescent cells not only lose function, but interfere with processes that create new cells when old ones die. They also harm nearby healthy cells by secreting pro-inflammatory factors and other tissue-damaging molecules.
Senescent cells don’t normally form before we’re past the age of 60, but they can arise in obese individuals and those with chronic diseases at a much earlier age. Whatever the reason you develop these “zombie cells” that refuse to die, they drive the aging […]